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Sterile splenic abscesses in systemic Weber-Christian disease

Identifieur interne : 003337 ( Main/Exploration ); précédent : 003336; suivant : 003338

Sterile splenic abscesses in systemic Weber-Christian disease

Auteurs : Douglas E. Lemley [États-Unis] ; Byungkyu Chun [États-Unis] ; Thomas R. Cupps [États-Unis]

Source :

RBID : ISTEX:35EAB9FFF5A01762D141A8DFF4A825554F04EA49

English descriptors

Abstract

Abstract: A patient with Weber-Christian disease and relapsing abdominal pain due to sterile splenic abscesses is presented. Histologically, acute and chronic inflammation with focal suppurative infiltrates of phagocytosed fat was detected in the absence of vascular or embolic disease, infection, or other apparent cause. Abdominal discomfort, an uncommon manifestation of Weber-Christian disease, usually is related to mesenteric panniculitis. Sterile splenic abscesses represent a previously undescribed complication of Weber-Christian disease, and another source of abdominal pain in this disorder. Although the precise pathophysiology of sterile splenic abscess formation in Weber-Christian disease is unknown, splenectomy is an effective means of alleviating pain.

Url:
DOI: 10.1016/0002-9343(87)90773-X


Affiliations:


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Le document en format XML

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<term>Bowel ischemia</term>
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<div type="abstract" xml:lang="en">Abstract: A patient with Weber-Christian disease and relapsing abdominal pain due to sterile splenic abscesses is presented. Histologically, acute and chronic inflammation with focal suppurative infiltrates of phagocytosed fat was detected in the absence of vascular or embolic disease, infection, or other apparent cause. Abdominal discomfort, an uncommon manifestation of Weber-Christian disease, usually is related to mesenteric panniculitis. Sterile splenic abscesses represent a previously undescribed complication of Weber-Christian disease, and another source of abdominal pain in this disorder. Although the precise pathophysiology of sterile splenic abscess formation in Weber-Christian disease is unknown, splenectomy is an effective means of alleviating pain.</div>
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